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Nathan J. Sniadecki
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Journal Articles

Nonmuscle Myosin IIA Regulates Platelet Contractile Forces Through Rho Kinase and Myosin Light-Chain Kinase

Shirin Feghhi, Wes W. Tooley, Nathan J. Sniadecki
Journal: Journal of Biomechanical Engineering
Article Type: Technical Briefs
J Biomech Eng. October 2016, 138(10): 104506.
Paper No: BIO-15-1497
DOI: https://doi.org/10.1115/1.4034489
Published Online: September 1, 2016
View Article titled, Nonmuscle Myosin IIA Regulates Platelet Contractile Forces Through Rho Kinase and Myosin Light-Chain Kinase
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Journal Articles

Measuring the Contractile Forces of Human Induced Pluripotent Stem Cell-Derived Cardiomyocytes With Arrays of Microposts

Marita L. Rodriguez, Brandon T. Graham, Lil M. Pabon, Sangyoon J. Han, Charles E. Murry, Nathan J. Sniadecki
Journal: Journal of Biomechanical Engineering
Article Type: Research-Article
J Biomech Eng. May 2014, 136(5): 051005.
Paper No: BIO-13-1381
DOI: https://doi.org/10.1115/1.4027145
Published Online: April 10, 2014
View Article titled, Measuring the Contractile Forces of Human Induced Pluripotent Stem Cell-Derived Cardiomyocytes With Arrays of Microposts
Click here to open pdf in another window PDF for Measuring the Contractile Forces of Human Induced Pluripotent Stem Cell-Derived Cardiomyocytes With Arrays of Microposts
Topics: Coatings, Deflection, Diseases, Microscopy, Proteins, Relaxation (Physics), Stiffness, Imaging, Tension, Statistical analysis
Proceedings Papers

Cellular Mechanotransduction Studies Using Microposts, Nanoposts, and Magnetic Posts

Nathan J. Sniadecki
Proc. ASME. SBC2008, ASME 2008 Summer Bioengineering Conference, Parts A and B, 1047-1048, June 25–29, 2008
Paper No: SBC2008-192465
DOI: https://doi.org/10.1115/SBC2008-192465
View Paper titled, Cellular Mechanotransduction Studies Using Microposts, Nanoposts, and Magnetic Posts
Click here to open pdf in another window PDF for Cellular Mechanotransduction Studies Using Microposts, Nanoposts, and Magnetic Posts
Topics: Biology, Control equipment, Microfabrication, Nanotechnology, Probes, Tension, Traction
Proceedings Papers

Platelet Retraction Forces Induced Under High Shear Gradient Activation

Lucas H. Ting, Shirin Feghhi, Nathan J. Sniadecki
Proc. ASME. SBC2013, Volume 1B: Extremity; Fluid Mechanics; Gait; Growth, Remodeling, and Repair; Heart Valves; Injury Biomechanics; Mechanotransduction and Sub-Cellular Biophysics; MultiScale Biotransport; Muscle, Tendon and Ligament; Musculoskeletal Devices; Multiscale Mechanics; Thermal Medicine; Ocular Biomechanics; Pediatric Hemodynamics; Pericellular Phenomena; Tissue Mechanics; Biotransport Design and Devices; Spine; Stent Device Hemodynamics; Vascular Solid Mechanics; Student Paper and Design Competitions, V01BT49A003, June 26–29, 2013
Paper No: SBC2013-14211
DOI: https://doi.org/10.1115/SBC2013-14211
View Paper titled, Platelet Retraction Forces Induced Under High Shear Gradient Activation
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Topics: Platelets, Shear (Mechanics), Vessels, Blood vessels, Hemodynamics, Shear rate, Stents, Valves
Proceedings Papers

Observation of Traction Forces During Galvanotaxis

Nikita Taparia, Nathan J. Sniadecki
Proc. ASME. SBC2013, Volume 1B: Extremity; Fluid Mechanics; Gait; Growth, Remodeling, and Repair; Heart Valves; Injury Biomechanics; Mechanotransduction and Sub-Cellular Biophysics; MultiScale Biotransport; Muscle, Tendon and Ligament; Musculoskeletal Devices; Multiscale Mechanics; Thermal Medicine; Ocular Biomechanics; Pediatric Hemodynamics; Pericellular Phenomena; Tissue Mechanics; Biotransport Design and Devices; Spine; Stent Device Hemodynamics; Vascular Solid Mechanics; Student Paper and Design Competitions, V01BT62A010, June 26–29, 2013
Paper No: SBC2013-14670
DOI: https://doi.org/10.1115/SBC2013-14670
View Paper titled, Observation of Traction Forces During Galvanotaxis
Click here to open pdf in another window PDF for Observation of Traction Forces During Galvanotaxis
Topics: Cancer, Diseases, Traction
Proceedings Papers

E-Beam Nanopost Arrays Reveal That Glycoprotein Ib-IV-X Complex and Von Willebrand Factor Interactions Transmit Platelet Cytoskeletal Forces

Shirin Feghhi, Adam D. Munday, Wes W. Tooley, Jose A. Lopez, Nathan J. Sniadecki
Proc. ASME. SBC2013, Volume 1B: Extremity; Fluid Mechanics; Gait; Growth, Remodeling, and Repair; Heart Valves; Injury Biomechanics; Mechanotransduction and Sub-Cellular Biophysics; MultiScale Biotransport; Muscle, Tendon and Ligament; Musculoskeletal Devices; Multiscale Mechanics; Thermal Medicine; Ocular Biomechanics; Pediatric Hemodynamics; Pericellular Phenomena; Tissue Mechanics; Biotransport Design and Devices; Spine; Stent Device Hemodynamics; Vascular Solid Mechanics; Student Paper and Design Competitions, V01BT50A004, June 26–29, 2013
Paper No: SBC2013-14694
DOI: https://doi.org/10.1115/SBC2013-14694
View Paper titled, E-Beam Nanopost Arrays Reveal That Glycoprotein Ib-IV-X Complex and Von Willebrand Factor Interactions Transmit Platelet Cytoskeletal Forces
Click here to open pdf in another window PDF for E-Beam Nanopost Arrays Reveal That Glycoprotein Ib-IV-X Complex and Von Willebrand Factor Interactions Transmit Platelet Cytoskeletal Forces
Topics: Cathode rays, Electron beams, Platelets, Adhesion, Nanoscale phenomena, Plasma desorption mass spectrometry, Proteins
Proceedings Papers

Cellular Traction Forces Measured With Microposts Made by Hot Embossing of Polystyrene

Kevin S. Bielawski, Nathan J. Sniadecki
Proc. ASME. SBC2013, Volume 1A: Abdominal Aortic Aneurysms; Active and Reactive Soft Matter; Atherosclerosis; BioFluid Mechanics; Education; Biotransport Phenomena; Bone, Joint and Spine Mechanics; Brain Injury; Cardiac Mechanics; Cardiovascular Devices, Fluids and Imaging; Cartilage and Disc Mechanics; Cell and Tissue Engineering; Cerebral Aneurysms; Computational Biofluid Dynamics; Device Design, Human Dynamics, and Rehabilitation; Drug Delivery and Disease Treatment; Engineered Cellular Environments, V01AT17A021, June 26–29, 2013
Paper No: SBC2013-14568
DOI: https://doi.org/10.1115/SBC2013-14568
View Paper titled, Cellular Traction Forces Measured With Microposts Made by Hot Embossing of Polystyrene
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Topics: Embossing, Traction, Plasma desorption mass spectrometry, Adhesion, Coatings, Flow (Dynamics), Glass transition, Hardening (Curing), Pressure, Proteins
Proceedings Papers

Assessment of Induced Pluripotent Stem Cell-Derived Cardiomyocyte Contractility Using Micropost Arrays

Marita L. Rodriguez, Charles E. Murry, Nathan J. Sniadecki
Proc. ASME. SBC2013, Volume 1A: Abdominal Aortic Aneurysms; Active and Reactive Soft Matter; Atherosclerosis; BioFluid Mechanics; Education; Biotransport Phenomena; Bone, Joint and Spine Mechanics; Brain Injury; Cardiac Mechanics; Cardiovascular Devices, Fluids and Imaging; Cartilage and Disc Mechanics; Cell and Tissue Engineering; Cerebral Aneurysms; Computational Biofluid Dynamics; Device Design, Human Dynamics, and Rehabilitation; Drug Delivery and Disease Treatment; Engineered Cellular Environments, V01AT15A005, June 26–29, 2013
Paper No: SBC2013-14640
DOI: https://doi.org/10.1115/SBC2013-14640
View Paper titled, Assessment of Induced Pluripotent Stem Cell-Derived Cardiomyocyte Contractility Using Micropost Arrays
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Topics: Assaying, Biological tissues, Cardiovascular system, Fibers, Force measurement, Intrusion prevention systems, Patient treatment, Stem cells, Stress
Journal Articles

Review on Cell Mechanics: Experimental and Modeling Approaches

Marita L. Rodriguez, Patrick J. McGarry, Nathan J. Sniadecki
Journal: Applied Mechanics Reviews
Article Type: Review Articles
Appl. Mech. Rev. November 2013, 65(6): 060801.
Paper No: AMR-12-1063
DOI: https://doi.org/10.1115/1.4025355
Published Online: October 15, 2013
View Article titled, Review on Cell Mechanics: Experimental and Modeling Approaches
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Topics: Cellular mechanics, Drops, Fibers, Manufacturing, Simulation, Stiffness, Stress, Traction, Engineering simulation, Proteins
Proceedings Papers

The Coupled Influences of Substrate Stiffness and Cell Spreading Area on Traction Force

Sangyoon Han, Nathan J. Sniadecki
Proc. ASME. SBC2009, ASME 2009 Summer Bioengineering Conference, Parts A and B, 1079-1080, June 17–21, 2009
Paper No: SBC2009-206523
DOI: https://doi.org/10.1115/SBC2009-206523
View Paper titled, The Coupled Influences of Substrate Stiffness and Cell Spreading Area on Traction Force
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Topics: Stiffness, Traction, Feedback, Geometry, Polymerization, Probes, Stability, Tension
Proceedings Papers

Microposts With Embedded Nanowires to Control Substrate Stiffness

Kevin S. Bielawski, Nathan J. Sniadecki
Proc. ASME. SBC2012, ASME 2012 Summer Bioengineering Conference, Parts A and B, 1165-1166, June 20–23, 2012
Paper No: SBC2012-80791
DOI: https://doi.org/10.1115/SBC2012-80791
View Paper titled, Microposts With Embedded Nanowires to Control Substrate Stiffness
Click here to open pdf in another window PDF for Microposts With Embedded Nanowires to Control Substrate Stiffness
Topics: Nanowires, Stiffness, Nickel, Polymers
Proceedings Papers

Hemodynamic Shear Regulates Intercellular Forces and Permeability of Endothelial Cell Monolayers

Lucas H. Ting, Nathan J. Sniadecki
Proc. ASME. SBC2012, ASME 2012 Summer Bioengineering Conference, Parts A and B, 485-486, June 20–23, 2012
Paper No: SBC2012-80789
DOI: https://doi.org/10.1115/SBC2012-80789
View Paper titled, Hemodynamic Shear Regulates Intercellular Forces and Permeability of Endothelial Cell Monolayers
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Topics: Endothelial cells, Hemodynamics, Permeability, Shear (Mechanics), Biological tissues, Flow (Dynamics), Atherosclerosis, Bifurcation, Blood, Blood flow
Proceedings Papers

The Role of Nonmuscle Myosin IIA Regulation in Platelet Forces Using Microposts and Multiphysics Modeling

Shirin Feghhi, Nathan J. Sniadecki
Proc. ASME. SBC2011, ASME 2011 Summer Bioengineering Conference, Parts A and B, 961-962, June 22–25, 2011
Paper No: SBC2011-53905
DOI: https://doi.org/10.1115/SBC2011-53905
View Paper titled, The Role of Nonmuscle Myosin IIA Regulation in Platelet Forces Using Microposts and Multiphysics Modeling
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Topics: Modeling, Platelets, Physics
Proceedings Papers

A Multi-Physics Finite Element Model of the Traction Forces in a Three-Dimensional Smooth Muscle Cell

Marita L. Rodriguez, Sangyoon J. Han, Nathan J. Sniadecki
Proc. ASME. SBC2011, ASME 2011 Summer Bioengineering Conference, Parts A and B, 963-964, June 22–25, 2011
Paper No: SBC2011-53944
DOI: https://doi.org/10.1115/SBC2011-53944
View Paper titled, A Multi-Physics Finite Element Model of the Traction Forces in a Three-Dimensional Smooth Muscle Cell
Click here to open pdf in another window PDF for A Multi-Physics Finite Element Model of the Traction Forces in a Three-Dimensional Smooth Muscle Cell
Topics: Finite element model, Muscle, Physics, Traction, Aneurysms, Atherosclerosis, Blood flow, Bridges (Structures), Cardiovascular system, Diseases
Proceedings Papers

The Role of Thrombin, Fibrinogen, and Fibronectin on Platelet Clot Retraction Forces Analyzed Using Microposts

Xin M. Liang, Dayong Gao, Nathan J. Sniadecki
Proc. ASME. SBC2010, ASME 2010 Summer Bioengineering Conference, Parts A and B, 151-152, June 16–19, 2010
Paper No: SBC2010-19614
DOI: https://doi.org/10.1115/SBC2010-19614
View Paper titled, The Role of Thrombin, Fibrinogen, and Fibronectin on Platelet Clot Retraction Forces Analyzed Using Microposts
Click here to open pdf in another window PDF for The Role of Thrombin, Fibrinogen, and Fibronectin on Platelet Clot Retraction Forces Analyzed Using Microposts
Topics: Platelets, Thrombosis, Adhesion, Adhesives, Blood flow, Blood vessels, Bridges (Structures), Leakage, Shapes
Proceedings Papers

Thermal Fracture of Oxidized Polydimethylsiloxane and its Implications in Soft Lithography

Wes W. Tooley, Shirin Feghhi, Sangyoon J. Han, Junlan Wang, Nathan J. Sniadecki
Proc. ASME. IMECE2011, Volume 11: Nano and Micro Materials, Devices and Systems; Microsystems Integration, 27-35, November 11–17, 2011
Paper No: IMECE2011-64477
DOI: https://doi.org/10.1115/IMECE2011-64477
View Paper titled, Thermal Fracture of Oxidized Polydimethylsiloxane and its Implications in Soft Lithography
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Topics: Fracture (Materials), Lithography, Plasma desorption mass spectrometry, Temperature, Silicon, Surface cracks, Finite element analysis, Fracture toughness, Hardening (Curing), Manufacturing
Proceedings Papers

Traction Forces During Cell Migration Predicted by the Multiphysics Model

Sangyoon J. Han, Nathan J. Sniadecki
Proc. ASME. IMECE2011, Volume 8: Mechanics of Solids, Structures and Fluids; Vibration, Acoustics and Wave Propagation, 219-227, November 11–17, 2011
Paper No: IMECE2011-63843
DOI: https://doi.org/10.1115/IMECE2011-63843
View Paper titled, Traction Forces During Cell Migration Predicted by the Multiphysics Model
Click here to open pdf in another window PDF for Traction Forces During Cell Migration Predicted by the Multiphysics Model
Topics: Traction, Adhesion, Engineering simulation, Signals, Simulation, Tension, Cycles, Dynamics (Mechanics), Fibers, Manufacturing
Journal Articles

Effect of Silanization Film Thickness in Soft Lithography of Nanoscale Features

Lucas H. Ting, Shirin Feghhi, Sangyoon J. Han, Marita L. Rodriguez, Nathan J. Sniadecki
Journal: Journal of Nanotechnology in Engineering and Medicine
Article Type: Research Papers
J. Nanotechnol. Eng. Med. November 2011, 2(4): 041006.
DOI: https://doi.org/10.1115/1.4005665
Published Online: April 4, 2012
View Article titled, Effect of Silanization Film Thickness in Soft Lithography of Nanoscale Features
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Topics: Dimensions, Electron beams, Lithography, Nanoscale phenomena, Plasma desorption mass spectrometry, Plasmas (Ionized gases), Silicon, Cathode rays, Film thickness
Proceedings Papers

Platelet Nano-Forces are Similar on Fibronectin and Fibrinogen Ligands

Xin M. Liang, Nathan J. Sniadecki
Proc. ASME. NEMB2010, ASME 2010 First Global Congress on NanoEngineering for Medicine and Biology, 55-56, February 7–10, 2010
Paper No: NEMB2010-13278
DOI: https://doi.org/10.1115/NEMB2010-13278
View Paper titled, Platelet Nano-Forces are Similar on Fibronectin and Fibrinogen Ligands
Click here to open pdf in another window PDF for Platelet Nano-Forces are Similar on Fibronectin and Fibrinogen Ligands
Topics: Platelets, Biomechanics, Blood flow, Nanoscale phenomena, Stability, Thrombosis