Traditional reliability analysis generally uses probability approach to quantify the uncertainty, while it needs a great amount of information to construct precise distributions of the uncertain parameters. In this paper, a new reliability analysis technique is developed based on a hybrid uncertain model, which can deal with problems with limited information. All uncertain parameters are treated as random variables, while some of their distribution parameters are not given precise values but variation intervals. Due to the existence of the interval parameters, a limit-state strip enclosed by two bounding hyper-surfaces will be resulted in the transformed normal space, instead of a single hyper-surface as we usually obtain in conventional reliability analysis. All the limit-state strips are then summarized into two different classes and corresponding reliability analysis models are proposed for them. A monotonicity analysis is carried out for probability transformations of the random variables, through which effects of the interval distribution parameters on the limit state can be well revealed. Based on the monotonicity analysis, two algorithms are then formulated to solve the proposed hybrid reliability models. Three numerical examples are investigated to demonstrate the effectiveness of the present method.