Ammonia borane (AB) is deemed to be the most promising energy storage material with varieties of exceptional properties, most reports mainly discuss its application in hydrogen storage and release as the hydrogen storage materials, which intends to address the hydrogen storage issues of on-board hydrogen fuel cell. However, some other promising applications of AB have also been confirmed by researchers, although these applications have not been intensively studied like its application of hydrogen storage materials. The article mainly introduce the synthesis, dehydrogenation (themolysis, hydrolysis, and methanolysis), and regeneration of AB and highlight the applications in green propulsion system of rocket, portable hydrogen source for on-board fuel cell, chemical catalysis, and electrochemical energy systems. In the meantime, the main achievements, current developments, limitations, and challenges in AB for advanced energy technology applications are briefly discussed. This article will provide inspiration for expanding the application of AB in the future.