... was formulated to analyze growth and remodeling in living biological tissues. It can also reproduce and extend classical frameworks of damage mechanics and viscoelasticity under isothermal conditions, when modeling bonds that can break and reform. This study focuses on establishing the thermodynamic foundations...

...Abhijit Dutta; Himadri Chattopadhyay Thermodynamics, the science of energy interactions, governs the direction of processes found in nature. While the subject finds wide applications in science and technology, its connection to biological sciences and in particular to bio-engineering is becoming...

... Zealand rabbit Achilles tendons. We presented a local formulation of thermodynamic evolution outside equilibrium at a representative element volume scale to describe the tendon’s macroscopic behavior based on the notion of relaxed stress. It was shown that the model corresponds quite well...

... with minimal damage to normal tissue. Model simulations that predict the local effects of thermal ablation with specific power inputs online can assist the clinical decision-making process. tissue coagulation laser energy source thermal model MRI lesion size thermodynamics biological effects...

... the thermodynamic and kinetic aspects of protein stability in these crowded cellular or solution environments. We use a coarse-grained modeling approach to study the effects of different crowding agents on the conformational equilibria of proteins and the thermodynamic phase behavior of their solutions. At low...

... is the absolute temperature. However, this model is unable to capture transition phenomena over the entire hyperthermia and ablation temperature range, particularly during the initial stage of heating. Inspired by classical statistical thermodynamic principles, we propose a general two-state model to characterize...