...Abhay B. Ramachandra; Nicole Mikush; Maor Sauler; Jay D. Humphrey; Edward P. Manning Competent elastic fibers are critical to the function of the lung and right circulation. Murine models of elastopathies can aid in understanding the functional roles of the elastin and elastin-associated...

...P. Mythravaruni; Parag Ravindran Oxidation of aorta by hydroxyl radicals produces structural changes in arterial proteins like elastin and collagen. This in turn results in change in the mechanical response of aorta. In this paper, a thermodynamically consistent constitutive model is developed...

...Jessica E. Wagenseil Allometric scaling laws relate physiologic parameters to body weight. Genetically modified mice allow investigation of allometric scaling laws when fundamental cardiovascular components are altered. Elastin haploinsufficient (Eln +/− ) mice have reduced elastin amounts...

.... Currently, the model does not consider the concentric, circumferential layers of elastin, collagen, and smooth muscle, which form the medial lamellae [ 39 ]. Unlike the current study, which considers the failure of the fibers within the lamellae, a study with radial and shear loading would involve...

... of Collagen and Elastin in Normotensive Human Thoracic Aorta ,” Clin. Chim. Acta. , 245 ( 1 ), pp. 73 – 84 . 10.1016/0009-8981(95)06174-6 35 Sakuraoka , K. , Tajima , S. , Seyama , Y. , Teramoto , K. , and Ishibashi , M. , 1996 , “ Analysis of Connective Tissue Macromolecular...

... to model and predict the behavior under any load. Most ex vivo tests are performed within 24 h of dissection, so the tissue is still “alive.” For large elastic arteries; however, the passive mechanical behavior is attributed mostly to the very stable proteins, elastin, and collagen. If the testing...

...Silvia Wognum; David E. Schmidt; Michael S. Sacks The urinary bladder wall (UBW), which is composed of smooth muscle, collagen, and elastin, undergoes profound remodeling in response to changes in mechanical loading resulting from various pathologies. In our laboratory, we have observed...

... for the individual contribution of each major structural component (elastin, collagen, and vascular smooth muscle). However, none of the currently proposed structural models succeeded in simultaneously and accurately describing both the pressure-radius and pressure-longitudinal force curves. We have hypothesized...

... cardiovascular system biomechanics physiological models elasticity proteins molecular biophysics molecular configurations finite element method collagen elastin network The mechanical behavior of the arterial wall is central to hemodynamic and vascular health. Clinical treatments (e.g...

... parameters. 05 02 2005 16 11 2005 biomechanics neurophysiology muscle mechanoception strain energy function (SEF) material parameters collagen elastin The primary function of the esophagus is food transport facilitated by the peristaltic motion of muscle, which is mainly...

... and untreated TEBVs were measured following 1, 7, 15, 30, 45, and 60 days of treatment. At corresponding time points, the effect of these treatments on collagen and elastin protein synthesis and mRNA expression was examined. RA/AA treated TEBV strength increased and stiffness decreased compared to controls...