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Journal Articles

Non-Contact Irreversible Electroporation in the Esophagus With a Wet Electrode Approach

Mary Chase Sheehan, Scott Collins, Thomas Wimmer, Narendra Babu Gutta, Sebastian Monette, Jeremy C. Durack, Stephen B. Solomon, Govindarajan Srimathveeravalli
Journal: Journal of Biomechanical Engineering
Publisher: ASME
Article Type: Research-Article
J Biomech Eng. September 2023, 145(9): 091004.
Paper No: BIO-22-1236
https://doi.org/10.1115/1.4062491
Published Online: May 22, 2023
View Article titled, Non-Contact Irreversible Electroporation in the Esophagus With a Wet Electrode Approach
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Topics: Ablation (Vaporization technology), Biological tissues, Damage, Electrodes, Electroporation, Simulation, Tumors, Wire, Catheters, Electric fields
Includes: Supplementary data
Journal Articles

Lethal Electric Field Thresholds for Cerebral Cells With Irreversible Electroporation and H-FIRE Protocols: An In Vitro Three-Dimensional Cell Model Study

Ting Shu, Lujia Ding, Zheng Fang, Shuangquan Yu, Lingchao Chen, Michael A. J. Moser, Wenjun Zhang, Zhiyong Qin, Bing Zhang
Journal: Journal of Biomechanical Engineering
Publisher: ASME
Article Type: Research-Article
J Biomech Eng. October 2022, 144(10): 101010.
Paper No: BIO-22-1024
https://doi.org/10.1115/1.4054381
Published Online: May 12, 2022
View Article titled, Lethal Electric Field Thresholds for Cerebral Cells With Irreversible Electroporation and H-FIRE Protocols: An In Vitro Three-Dimensional Cell Model Study
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Topics: Ablation (Vaporization technology), Electric fields, Electrical conductivity, Electroporation, Fire, Temperature, Tumors, Brain
Journal Articles

Experimental and Numerical Investigation of Parameters Affecting High-Frequency Irreversible Electroporation for Prostate Cancer Ablation

Kenneth N. Aycock, Ram Anand Vadlamani, Edward J. Jacobs, IV, Khan Mohammad Imran, Scott S. Verbridge, Irving C. Allen, Navid Manuchehrabadi, Rafael V. Davalos
Journal: Journal of Biomechanical Engineering
Publisher: ASME
Article Type: Research-Article
J Biomech Eng. June 2022, 144(6): 061003.
Paper No: BIO-21-1372
https://doi.org/10.1115/1.4053595
Published Online: February 15, 2022
View Article titled, Experimental and Numerical Investigation of Parameters Affecting High-Frequency Irreversible Electroporation for Prostate Cancer Ablation
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Topics: Ablation (Vaporization technology), Biological tissues, Cancer, Damage, Delays, Electric fields, Electroporation, Fire, Tumors, Performance
Includes: Supplementary data
Journal Articles

Electroporation-Based Therapy for Brain Tumors: A Review

Zheng Fang, Lingchao Chen, Michael A. J. Moser, Wenjun Zhang, Zhiyong Qin, Bing Zhang
Journal: Journal of Biomechanical Engineering
Publisher: ASME
Article Type: Review Articles
J Biomech Eng. October 2021, 143(10): 100802.
Paper No: BIO-21-1079
https://doi.org/10.1115/1.4051184
Published Online: June 17, 2021
View Article titled, Electroporation-Based Therapy for Brain Tumors: A Review
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Topics: Brain, Electroporation, Patient treatment, Tumors, Ablation (Vaporization technology), Electric fields, Blood, Membranes
Journal Articles

Treatment Planning Optimization in Irreversible Electroporation for Complete Ablation of Variously Sized Cervical Tumors: A Numerical Study

Lujia Ding, Michael Moser, Yigang Luo, Wenjun Zhang, Bing Zhang
Journal: Journal of Biomechanical Engineering
Publisher: ASME
Article Type: Technical Briefs
J Biomech Eng. January 2021, 143(1): 014503.
Paper No: BIO-20-1087
https://doi.org/10.1115/1.4047551
Published Online: September 29, 2020
View Article titled, Treatment Planning Optimization in Irreversible Electroporation for Complete Ablation of Variously Sized Cervical Tumors: A Numerical Study
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Topics: Ablation (Vaporization technology), Electroporation, Tumors, Optimization, Electrodes, Modeling, Biological tissues
Journal Articles

The Role of Protein Loss and Denaturation in Determining Outcomes of Heating, Cryotherapy, and Irreversible Electroporation on Cardiomyocytes

Feng Liu, Priyatanu Roy, Qi Shao, Chunlan Jiang, Jeunghwan Choi, Connie Chung, Dushyant Mehra, John C. Bischof
Journal: Journal of Biomechanical Engineering
Publisher: ASME
Article Type: Research-Article
J Biomech Eng. June 2018, 140(6): 061007.
Paper No: BIO-17-1226
https://doi.org/10.1115/1.4039375
Published Online: April 2, 2018
View Article titled, The Role of Protein Loss and Denaturation in Determining Outcomes of Heating, Cryotherapy, and Irreversible Electroporation on Cardiomyocytes
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Topics: Heating, Proteins, Temperature, Electroporation
Includes: Supplementary data
Journal Articles

Macroscopic Modeling of In Vivo Drug Transport in Electroporated Tissue

Bradley Boyd, Sid Becker
Journal: Journal of Biomechanical Engineering
Publisher: ASME
Article Type: Research-Article
J Biomech Eng. March 2016, 138(3): 031008.
Paper No: BIO-15-1359
https://doi.org/10.1115/1.4032380
Published Online: February 5, 2016
View Article titled, Macroscopic Modeling of In Vivo Drug Transport in Electroporated Tissue
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Topics: Biological tissues, Drugs, Electrical conductivity, Electroporation, Electric fields, Transients (Dynamics)
Journal Articles

Experimental Factors to Be Considered in Electroporation-Mediated Transdermal Diffusion Experiments

Nataša Pavšelj, Barbara Zorec, Damijan Miklavčič, Sid Becker
Journal: Journal of Biomechanical Engineering
Publisher: ASME
Article Type: Technical Briefs
J Biomech Eng. December 2015, 137(12): 124501.
Paper No: BIO-15-1353
https://doi.org/10.1115/1.4031767
Published Online: October 27, 2015
View Article titled, Experimental Factors to Be Considered in Electroporation-Mediated Transdermal Diffusion Experiments
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Topics: Diffusion (Physics), Electroporation, Shapes, Skin, Electrodes, Vickers hardness testing, Temperature, Heating
Journal Articles

2014 Richard Skalak Award

Journal: Journal of Biomechanical Engineering
Publisher: ASME
Article Type: Editorial
J Biomech Eng. February 2015, 137(2): 020205.
Paper No: BIO-14-1589
https://doi.org/10.1115/1.4029298
Published Online: February 1, 2015
View Article titled, 2014 Richard Skalak Award
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Topics: Ablation (Vaporization technology), Bearings, Bioengineering, Biological tissues, Biomechanical engineering, Biomechanics, Biomedical engineering, Blood vessels, Cell membranes, Computer simulation
Journal Articles

The Effect of Small Intestine Heterogeneity on Irreversible Electroporation Treatment Planning

Mary Phillips
Journal: Journal of Biomechanical Engineering
Publisher: ASME
Article Type: Research-Article
J Biomech Eng. September 2014, 136(9): 091009.
Paper No: BIO-14-1086
https://doi.org/10.1115/1.4027815
Published Online: July 16, 2014
View Article titled, The Effect of Small Intestine Heterogeneity on Irreversible Electroporation Treatment Planning
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Topics: Biological tissues, Electric fields, Electrical conductivity, Electroporation, Damage, Ablation (Vaporization technology)
Journal Articles

2013 Editors' Choice Papers

Journal: Journal of Biomechanical Engineering
Publisher: ASME
Article Type: Editorial
J Biomech Eng. February 2014, 136(2): 020204.
Paper No: BIO-13-1581
https://doi.org/10.1115/1.4026404
Published Online: February 5, 2014
View Article titled, 2013 Editors' Choice Papers
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Topics: Aneurysms, Anisotropy, Biological tissues, Biomechanics, Bone, Computer simulation, Damage, Deformation, Electrodes, Electroporation
Journal Articles

An Experimental and Numerical Investigation of Phase Change Electrodes for Therapeutic Irreversible Electroporation

Christopher B. Arena, Roop L. Mahajan, Marissa Nichole Rylander, Rafael V. Davalos
Journal: Journal of Biomechanical Engineering
Publisher: ASME
Article Type: Research-Article
J Biomech Eng. November 2013, 135(11): 111009.
Paper No: BIO-13-1182
https://doi.org/10.1115/1.4025334
Published Online: October 3, 2013
View Article titled, An Experimental and Numerical Investigation of Phase Change Electrodes for Therapeutic Irreversible Electroporation
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Topics: Electrodes, Electroporation, Temperature, Biological tissues, Gallium, Melting point
Journal Articles

Nonthermal Irreversible Electroporation for Tissue Decellularization

Mary Phillips, Elad Maor, Boris Rubinsky
Journal: Journal of Biomechanical Engineering
Publisher: ASME
Article Type: Research Papers
J Biomech Eng. September 2010, 132(9): 091003.
https://doi.org/10.1115/1.4001882
Published Online: August 16, 2010
View Article titled, Nonthermal Irreversible Electroporation for Tissue Decellularization
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Topics: Biological tissues, Damage, Electroporation, Tissue scaffolds, Finite element analysis, Tissue engineering, Carotid arteries
Journal Articles

Endovascular Nonthermal Irreversible Electroporation: A Finite Element Analysis

Elad Maor, Boris Rubinsky
Journal: Journal of Biomechanical Engineering
Publisher: ASME
Article Type: Research Papers
J Biomech Eng. March 2010, 132(3): 031008.
https://doi.org/10.1115/1.4001035
Published Online: February 17, 2010
View Article titled, Endovascular Nonthermal Irreversible Electroporation: A Finite Element Analysis
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Topics: Biological tissues, Damage, Electric fields, Electrodes, Electroporation, Finite element analysis, Temperature, Transients (Dynamics), Ablation (Vaporization technology), Blood
Journal Articles

Electrical Field and Temperature Model of Nonthermal Irreversible Electroporation in Heterogeneous Tissues

Charlotte Daniels, Boris Rubinsky
Journal: Journal of Biomechanical Engineering
Publisher: ASME
Article Type: Research Papers
J Biomech Eng. July 2009, 131(7): 071006.
https://doi.org/10.1115/1.3156808
Published Online: July 16, 2009
View Article titled, Electrical Field and Temperature Model of Nonthermal Irreversible Electroporation in Heterogeneous Tissues
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Topics: Biological tissues, Electric fields, Electroporation, Temperature, Blood vessels, Tumors, Surgery, Electrodes, Ducts, Temperature distribution
Journal Articles

A Preliminary Study to Delineate Irreversible Electroporation From Thermal Damage Using the Arrhenius Equation

Hadi Shafiee, Paulo A. Garcia, Rafael V. Davalos
Journal: Journal of Biomechanical Engineering
Publisher: ASME
Article Type: Technical Briefs
J Biomech Eng. July 2009, 131(7): 074509.
https://doi.org/10.1115/1.3143027
Published Online: June 12, 2009
View Article titled, A Preliminary Study to Delineate Irreversible Electroporation From Thermal Damage Using the Arrhenius Equation
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Topics: Biological tissues, Damage, Electroporation, Electric fields, Heating, Joules
Journal Articles

Local Temperature Rises Influence In Vivo Electroporation Pore Development: A Numerical Stratum Corneum Lipid Phase Transition Model

S. M. Becker, A. V. Kuznetsov
Journal: Journal of Biomechanical Engineering
Publisher: ASME
Article Type: Technical Papers
J Biomech Eng. October 2007, 129(5): 712–721.
https://doi.org/10.1115/1.2768380
Published Online: March 7, 2007
View Article titled, Local Temperature Rises Influence In Vivo Electroporation Pore Development: A Numerical Stratum Corneum Lipid Phase Transition Model
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Topics: Electroporation, Heating, Joules, Melting, Phase transitions, Skin, Temperature, Composite materials, Heat, Current density
Journal Articles

Numerical Assessment of Thermal Response Associated With In Vivo Skin Electroporation: The Importance of the Composite Skin model

S. M. Becker, A. V. Kuznetsov
Journal: Journal of Biomechanical Engineering
Publisher: ASME
Article Type: Technical Papers
J Biomech Eng. June 2007, 129(3): 330–340.
https://doi.org/10.1115/1.2720910
Published Online: October 6, 2006
View Article titled, Numerical Assessment of Thermal Response Associated With In Vivo Skin Electroporation: The Importance of the Composite Skin model
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Topics: Biological tissues, Composite materials, Damage, Electroporation, Skin, Temperature, Joules, Electric fields, Electrical conductivity, Heating
Journal Articles

Numerical Modeling of In Vivo Plate Electroporation Thermal Dose Assessment

S. M. Becker, A. V. Kuznetsov
Journal: Journal of Biomechanical Engineering
Publisher: ASME
Article Type: Technical Papers
J Biomech Eng. February 2006, 128(1): 76–84.
https://doi.org/10.1115/1.2132375
Published Online: August 18, 2005
View Article titled, Numerical Modeling of In Vivo Plate Electroporation Thermal Dose Assessment
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Topics: Biological tissues, Blood, Blood vessels, Damage, Electric fields, Electrodes, Electroporation, Liver, Temperature, Vessels