Application of tibiofemoral compression force (TCF) has been shown to produce anterior cruciate ligament (ACL) injuries in a laboratory setting. A new robotic testing methodology was utilized to predict ACL forces generated by TCF without directly loading the ligament. We hypothesized that ACL force, directly recorded by a miniature load cell during an unconstrained test, could be predicted by measurements of anterior tibial restraining force (ARF) recorded during a constrained test. The knee was first flexed under load control with 25 N TCF (tibial displacements and rotations unconstrained) to record a baseline kinematic pathway. Tests were repeated with increasing levels of TCF, while recording ACL force and knee kinematics. Then tests with increasing TCF were performed under displacement control to reproduce the baseline kinematic pathway (tibia constrained), while recording ARF. This allowed testing to 1500 N TCF since the ACL was not loaded. TCF generated ACL force for all knees (n = 10) at 50 deg flexion, and for eight knees at 30 deg flexion (unconstrained test). ACL force (unconstrained test) and ARF (constrained test) had strong linear correlations with TCF at both flexion angles (R2 from 0.85 to 0.99), and ACL force was strongly correlated with ARF at both flexion angles (R2 from 0.76 to 0.99). Under 500 N TCF, the mean error between ACL force prediction from ARF regression and measured ACL force was 4.8±7.3 N at 30 deg and 8.8±27.5 N at 50 deg flexion. Our hypothesis was confirmed for TCF levels up to 500 N, and ARF had a strong linear correlation with TCF up to 1500 N TCF.
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December 2018
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Prediction of Anterior Cruciate Ligament Force Produced by Tibiofemoral Compression During Controlled Knee Flexion: A New Robotic Testing Methodology
Keith L. Markolf,
Keith L. Markolf
Biomechanics Research Section,
UCLA Department of Orthopaedic Surgery,
David Geffen School of Medicine,
1000 Veteran Avenue,
UCLA Rehabilitation Center, Room 21-67,
Los Angeles, CA 90095
e-mail: kmarkolf@mednet.ucla.edu
UCLA Department of Orthopaedic Surgery,
David Geffen School of Medicine,
1000 Veteran Avenue,
UCLA Rehabilitation Center, Room 21-67,
Los Angeles, CA 90095
e-mail: kmarkolf@mednet.ucla.edu
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Daniel V. Boguszewski,
Daniel V. Boguszewski
Biomechanics Research Section,
UCLA Department of Orthopaedic Surgery,
David Geffen School of Medicine,
1000 Veteran Avenue,
UCLA Rehabilitation Center, Room 21-67,
Los Angeles, CA 90095
UCLA Department of Orthopaedic Surgery,
David Geffen School of Medicine,
1000 Veteran Avenue,
UCLA Rehabilitation Center, Room 21-67,
Los Angeles, CA 90095
Search for other works by this author on:
Kent T. Yamaguchi, Jr.,
Kent T. Yamaguchi, Jr.
Biomechanics Research Section,
UCLA Department of Orthopaedic Surgery,
David Geffen School of Medicine,
UCLA Rehabilitation Center, Room 21-67,
Los Angeles, CA 90095
UCLA Department of Orthopaedic Surgery,
David Geffen School of Medicine,
1000 Veteran Avenue,
UCLA Rehabilitation Center, Room 21-67,
Los Angeles, CA 90095
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Christopher J. Lama,
Christopher J. Lama
Biomechanics Research Section,
UCLA Department of Orthopaedic Surgery,
David Geffen School of Medicine,
UCLA Rehabilitation Center, Room 21-67,
Los Angeles, CA 90095
UCLA Department of Orthopaedic Surgery,
David Geffen School of Medicine,
1000 Veteran Avenue
, UCLA Rehabilitation Center, Room 21-67,
Los Angeles, CA 90095
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David R. McAllister
David R. McAllister
Biomechanics Research Section,
UCLA Department of Orthopaedic Surgery,
David Geffen School of Medicine,
1000 Veteran Avenue,
UCLA Rehabilitation Center, Room 21-67,
Los Angeles, CA 90095
UCLA Department of Orthopaedic Surgery,
David Geffen School of Medicine,
1000 Veteran Avenue,
UCLA Rehabilitation Center, Room 21-67,
Los Angeles, CA 90095
Search for other works by this author on:
Keith L. Markolf
Biomechanics Research Section,
UCLA Department of Orthopaedic Surgery,
David Geffen School of Medicine,
1000 Veteran Avenue,
UCLA Rehabilitation Center, Room 21-67,
Los Angeles, CA 90095
e-mail: kmarkolf@mednet.ucla.edu
UCLA Department of Orthopaedic Surgery,
David Geffen School of Medicine,
1000 Veteran Avenue,
UCLA Rehabilitation Center, Room 21-67,
Los Angeles, CA 90095
e-mail: kmarkolf@mednet.ucla.edu
Daniel V. Boguszewski
Biomechanics Research Section,
UCLA Department of Orthopaedic Surgery,
David Geffen School of Medicine,
1000 Veteran Avenue,
UCLA Rehabilitation Center, Room 21-67,
Los Angeles, CA 90095
UCLA Department of Orthopaedic Surgery,
David Geffen School of Medicine,
1000 Veteran Avenue,
UCLA Rehabilitation Center, Room 21-67,
Los Angeles, CA 90095
Kent T. Yamaguchi, Jr.
Biomechanics Research Section,
UCLA Department of Orthopaedic Surgery,
David Geffen School of Medicine,
UCLA Rehabilitation Center, Room 21-67,
Los Angeles, CA 90095
UCLA Department of Orthopaedic Surgery,
David Geffen School of Medicine,
1000 Veteran Avenue,
UCLA Rehabilitation Center, Room 21-67,
Los Angeles, CA 90095
Christopher J. Lama
Biomechanics Research Section,
UCLA Department of Orthopaedic Surgery,
David Geffen School of Medicine,
UCLA Rehabilitation Center, Room 21-67,
Los Angeles, CA 90095
UCLA Department of Orthopaedic Surgery,
David Geffen School of Medicine,
1000 Veteran Avenue
, UCLA Rehabilitation Center, Room 21-67,
Los Angeles, CA 90095
David R. McAllister
Biomechanics Research Section,
UCLA Department of Orthopaedic Surgery,
David Geffen School of Medicine,
1000 Veteran Avenue,
UCLA Rehabilitation Center, Room 21-67,
Los Angeles, CA 90095
UCLA Department of Orthopaedic Surgery,
David Geffen School of Medicine,
1000 Veteran Avenue,
UCLA Rehabilitation Center, Room 21-67,
Los Angeles, CA 90095
1Corresponding author.
Manuscript received February 12, 2018; final manuscript received June 26, 2018; published online September 25, 2018. Assoc. Editor: Paul Rullkoetter.
J Biomech Eng. Dec 2018, 140(12): 124503 (6 pages)
Published Online: September 25, 2018
Article history
Received:
February 12, 2018
Revised:
June 26, 2018
Citation
Markolf, K. L., Boguszewski, D. V., Yamaguchi, K. T., Jr., Lama, C. J., and McAllister, D. R. (September 25, 2018). "Prediction of Anterior Cruciate Ligament Force Produced by Tibiofemoral Compression During Controlled Knee Flexion: A New Robotic Testing Methodology." ASME. J Biomech Eng. December 2018; 140(12): 124503. https://doi.org/10.1115/1.4040775
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