Osmotic pressure and associated residual stresses play important roles in cartilage development and biomechanical function. The curling behavior of articular cartilage was believed to be the combination of results from the osmotic pressure derived from fixed negative charges on proteoglycans and the structural and compositional and material property inhomogeneities within the tissue. In the present study, the in vitro swelling and curling behaviors of thin strips of cartilage were analyzed with a new structural model using the triphasic mixture theory with a collagen-proteoglycan solid matrix composed of a three-layered laminate with each layer possessing a distinct set of orthotropic properties. A conewise linear elastic matrix was also incorporated to account for the well-known tension-compression nonlinearity of the tissue. This model can account, for the first time, for the swelling-induced curvatures found in published experimental results on excised cartilage samples. The results suggest that for a charged-hydrated soft tissue, such as articular cartilage, the balance of proteoglycan swelling and the collagen restraining within the solid matrix is the origin of the in situ residual stress, and that the layered collagen ultrastructure, e.g., relatively dense and with high stiffness at the articular surface, play the dominate role in determining curling behaviors of such tissues.
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February 2010
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A Triphasic Orthotropic Laminate Model for Cartilage Curling Behavior: Fixed Charge Density Versus Mechanical Properties Inhomogeneity
Leo Q. Wan,
Leo Q. Wan
Department of Biomedical Engineering,
Columbia University
, New York, NY 10027
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X. Edward Guo,
X. Edward Guo
Department of Biomedical Engineering,
Columbia University
, New York, NY 10027
Search for other works by this author on:
Van C. Mow
Van C. Mow
Department of Biomedical Engineering,
e-mail: vcm1@columbia.edu
Columbia University
, New York, NY 10027
Search for other works by this author on:
Leo Q. Wan
Department of Biomedical Engineering,
Columbia University
, New York, NY 10027
X. Edward Guo
Department of Biomedical Engineering,
Columbia University
, New York, NY 10027
Van C. Mow
Department of Biomedical Engineering,
Columbia University
, New York, NY 10027e-mail: vcm1@columbia.edu
J Biomech Eng. Feb 2010, 132(2): 024504 (5 pages)
Published Online: January 29, 2010
Article history
Received:
May 9, 2009
Revised:
December 21, 2009
Posted:
January 5, 2010
Published:
January 29, 2010
Online:
January 29, 2010
Citation
Wan, L. Q., Guo, X. E., and Mow, V. C. (January 29, 2010). "A Triphasic Orthotropic Laminate Model for Cartilage Curling Behavior: Fixed Charge Density Versus Mechanical Properties Inhomogeneity." ASME. J Biomech Eng. February 2010; 132(2): 024504. https://doi.org/10.1115/1.4000942
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